Understanding how Powassan virus adapts to different hosts
Investigating the Genetic Determinants of Host-Specificity and Potential for Further Adaptation of Powassan Virus
This study is looking at how the Powassan virus changes when it infects different animals, like ticks and mammals, to help us understand how it spreads and how we can better prevent and treat tick-borne diseases.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Albany NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-11061190 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that determine how the Powassan virus, a tick-borne virus, adapts to various hosts, including ticks and mammals. By analyzing genetic variations in the virus and its hosts, the study aims to uncover the mechanisms behind host specificity and potential adaptations. Patients may benefit from insights gained about the virus's behavior, which could inform prevention and treatment strategies for tick-borne diseases. The research will involve collecting and analyzing samples from different host species to understand the virus's evolution and transmission.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals living in areas where Powassan virus is endemic, particularly those who have been exposed to ticks.
Not a fit: Patients who do not reside in endemic areas or have no history of tick exposure may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating infections caused by the Powassan virus.
How similar studies have performed: Other research has shown success in understanding tick-borne viruses through genetic analysis, suggesting that this approach could yield valuable insights.
Where this research is happening
Albany, United States
- State University of New York at Albany — Albany, United States (Active)
Researchers
- Principal investigator: Lange, Rachel — State University of New York at Albany
- Study coordinator: Lange, Rachel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.