Understanding how populations adapt through genetic analysis
Identifying complex modes of adaptation from population-genomic data
['FUNDING_OTHER'] · FLORIDA ATLANTIC UNIVERSITY · NIH-11136231
This study looks at how our genes change over time due to natural selection and other influences, helping us understand which parts of our DNA might lead to helpful traits, and this information could eventually improve personalized medicine and treatment options for you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA ATLANTIC UNIVERSITY (nih funded) |
| Locations | 1 site (BOCA RATON, UNITED STATES) |
| Trial ID | NIH-11136231 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic variations within populations are influenced by natural selection and other factors. By utilizing advanced statistical methods and machine learning, the study aims to identify specific regions of the genome that are undergoing positive selection, which can lead to beneficial traits in populations. The research also explores balancing selection, which helps maintain genetic diversity. Patients may benefit from insights gained about genetic adaptations that could inform personalized medicine and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with a keen interest in genetic factors influencing health and disease, particularly those from diverse genetic backgrounds.
Not a fit: Patients with conditions that are not influenced by genetic factors or those who do not have a genetic predisposition to diseases may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic adaptations, leading to improved treatments and preventive strategies for various diseases.
How similar studies have performed: Previous research has shown success in using similar statistical and machine learning approaches to uncover genetic adaptations, indicating a promising avenue for this study.
Where this research is happening
BOCA RATON, UNITED STATES
- FLORIDA ATLANTIC UNIVERSITY — BOCA RATON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DEGIORGIO, MICHAEL — FLORIDA ATLANTIC UNIVERSITY
- Study coordinator: DEGIORGIO, MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.