Understanding how platelets form clots and their roles in health and disease
Studies of Physiologic and Pathologic Platelet Plug Formation
['FUNDING_P01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10836485
This study is looking at how platelets, which are tiny cells in your blood that help with clotting and healing, work in both healthy and sick situations, especially in diseases like arterial vascular disease, to better understand their role in your body.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10836485 on ClinicalTrials.gov |
What this research studies
This research investigates the complex roles of platelets in both normal and pathological conditions, focusing on how they contribute to clot formation, inflammation, and tissue healing. By utilizing advanced biological methods, the research aims to fill existing knowledge gaps regarding platelet function and their involvement in various diseases, including arterial vascular disease. The project is divided into multiple components, each exploring different aspects of platelet biology, and is conducted at the University of Pennsylvania.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with cardiovascular diseases or conditions that affect platelet function.
Not a fit: Patients without any known platelet disorders or cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions related to abnormal platelet function, such as heart disease and stroke.
How similar studies have performed: Previous research has shown promising results in understanding platelet biology, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRASS, LAWRENCE F — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: BRASS, LAWRENCE F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.