Understanding how platelets contribute to blood clotting issues in preeclampsia
Platelet-mediated mechanisms of placental and systemic hypercoagulability in preeclampsia
This study is looking at how platelets behave in pregnant women with preeclampsia, a condition that can cause serious health issues for both moms and babies, to find out how low oxygen levels in the placenta might lead to problems with blood flow and clotting, with the hope of discovering new ways to help those affected.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Mississippi Med Ctr NIH-funded |
| Lab location | 1 site (Jackson, United States) |
| Project ID | NIH-10898077 on NIH RePORTER |
What this research studies
This research investigates the role of platelets in the condition known as preeclampsia, which affects a significant number of pregnancies and can lead to serious health complications for both mothers and babies. The study focuses on how low oxygen levels in the placenta can trigger the release of substances that affect blood vessel function and increase the risk of blood clots. By examining the mechanisms behind this hypercoagulable state, the research aims to uncover potential therapeutic targets that could improve outcomes for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals diagnosed with preeclampsia or those at high risk for developing this condition.
Not a fit: Patients who are not pregnant or those without a diagnosis of preeclampsia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that reduce the risks associated with preeclampsia, improving maternal and fetal health.
How similar studies have performed: Previous research has indicated that understanding platelet function in other thrombotic conditions has led to successful interventions, suggesting potential for similar success in this area.
Where this research is happening
Jackson, United States
- University of Mississippi Med Ctr — Jackson, United States (Active)
Researchers
- Principal investigator: Palei, Ana Carolina — University of Mississippi Med Ctr
- Study coordinator: Palei, Ana Carolina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.