Understanding how platelets and white blood cells interact during sepsis
Platelet-Leukocyte Interactions in Sepsis
['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-10902022
This study is looking at how platelets and white blood cells work together in people with sepsis, a serious infection, to better understand how the immune system is affected, which could lead to new ways to help patients recover.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10902022 on ClinicalTrials.gov |
What this research studies
This research focuses on the interactions between platelets and leukocytes in patients with sepsis, a severe infection that can lead to organ failure. The study involves recruiting sepsis patients to collect clinical data and isolate platelets for analysis. By examining how sepsis affects the immune response, particularly the presentation of antigens by platelets, the research aims to uncover mechanisms that contribute to immune dysfunction. The findings could help improve patient outcomes by informing new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sepsis who are receiving treatment.
Not a fit: Patients who do not have sepsis or are not currently undergoing treatment for sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients suffering from sepsis.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in sepsis, making this approach both relevant and potentially impactful.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RONDINA, MATTHEW THOMAS — UNIVERSITY OF UTAH
- Study coordinator: RONDINA, MATTHEW THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.