NIH-funded research R21 grant

Understanding how plant compounds improve health

Official title: Exploring the mechanisms underlying plant (poly)phenols bioactivity via integrating metabolomics and fluxomics

Funded at University of California Los Angeles · NIH-11039984 · Data updated 2026-11-12

This study is looking at how plant-based compounds called polyphenols can help improve health by reducing inflammation and fighting off damage in the body, and it's for anyone interested in natural ways to boost their well-being.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startApril 1, 2024
Project endMarch 31, 2026
Funding year2025
Award (this year)$174,059
NIH project number5R21AT012814-02
Project IDNIH-11039984 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals interested in improving their health through dietary changes or those with conditions that may benefit from antioxidant and anti-inflammatory treatments.

Less likely to help

Patients who do not consume plant-based foods or have allergies to specific polyphenol-rich foods may not benefit from this research.

What this research studies

This research investigates the health benefits of plant-based compounds known as polyphenols, which are believed to have antioxidant and anti-inflammatory properties. By analyzing how these compounds interact with metabolism in cells and animals, the study aims to uncover the mechanisms behind their health-promoting effects. The research will utilize innovative techniques to quantify the metabolic changes caused by these compounds and explore their potential as therapeutic agents, either alone or in combination with other treatments.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations or treatments that harness the health benefits of plant polyphenols.

How similar studies have gone: Previous research has shown promising results in understanding the health benefits of plant polyphenols, indicating that this approach has potential for success.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Park, Junyoung O. — University of California Los Angeles
  • Study coordinator: Park, Junyoung O.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.