Understanding How Plant-Based Foods Affect Health and Disease Risk

Biomarkers of Dietary Flavonoid Intake, Carbonyl Stress, and Metabolic Risk

NIH-funded research North Carolina Agri & Tech St Univ · NIH-10880282

This work aims to find better ways to measure how plant-based foods in our diet affect our risk for conditions like type 2 diabetes and heart disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorth Carolina Agri & Tech St Univ NIH-funded
Lab location1 site (Greensboro, United States)
Project IDNIH-10880282 on NIH RePORTER

What this research studies

We know that eating plant-based foods rich in compounds called flavonoids might lower the risk of chronic diseases, but it's hard to measure this accurately. This project looks for new biological markers in the body that can show how much flavonoid-rich food someone has eaten. It also explores how these foods might protect our bodies from harmful stress, potentially preventing conditions like type 2 diabetes and heart disease. By finding these markers, we hope to get a clearer picture of how diet truly impacts our long-term health.

Who could benefit from this research

Good fit: Individuals interested in how diet affects their risk for type 2 diabetes and cardiovascular diseases, and who might be willing to provide samples for biomarker analysis, could be ideal candidates.

Not a fit: Patients seeking immediate treatment or direct intervention for an existing condition may not directly benefit from this foundational research.

Why it matters

Potential benefit: If successful, this work could lead to more accurate ways to track dietary intake and understand how specific foods protect against chronic diseases, helping people make better health choices.

How similar studies have performed: While some studies suggest a link between flavonoid intake and lower disease risk, consistent and reliable biological markers for dietary flavonoids are not yet well-established, making this a novel approach.

Where this research is happening

Greensboro, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.