Understanding how placental cells interact with the uterus to affect pregnancy health.
Mapping inter-cellular trophoblast-decidual signaling to its effects on invasion related maternal-fetal diseases
This study is looking at how cells from the placenta communicate with the uterus and how these interactions might cause serious issues during pregnancy, like fetal growth problems and preeclampsia, to help find better treatments for expecting moms and their babies.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-11297766 on NIH RePORTER |
What this research studies
This research investigates the signaling between placental cells and the uterine environment, focusing on how these interactions can lead to serious maternal-fetal diseases. By studying the molecular mechanisms that control placental invasion into the uterus, the research aims to identify factors that contribute to conditions like fetal growth restriction and preeclampsia. The approach combines computational modeling with experimental validation to create a comprehensive understanding of these processes, which could lead to improved treatment strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals experiencing complications related to placental invasion, such as fetal growth restriction or preeclampsia.
Not a fit: Patients who are not pregnant or those without complications related to placental invasion may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for serious pregnancy complications related to placental invasion.
How similar studies have performed: Previous research has shown promise in understanding placental biology and its implications for maternal-fetal health, indicating that this approach could yield valuable insights.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Suhail, Yasir — University of Connecticut Sch of Med/dnt
- Study coordinator: Suhail, Yasir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.