NIH-funded research Fellowship grant

Understanding how physical activity affects pain in chronic pain treatments

Official title: Characterizing the relationship between objective physical activity and momentary pain in cognitive behavioral interventions for chronic pain

Funded at University of California, San Diego · NIH-10888901 · Data updated 2026-11-12

This study is looking at how staying active can affect pain levels in Veterans with chronic pain, using helpful techniques like Acceptance and Commitment Therapy and Cognitive Behavioral Therapy to see if they can improve the way pain and activity work together.

More Chronic Pain research and trials

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startAugust 1, 2023
Project endJuly 31, 2025
Funding year2024
Award (this year)$41,316
NIH project number5F31AT012424-02
Project IDNIH-10888901 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Veterans suffering from chronic pain who are seeking new ways to manage their condition.

Less likely to help

Patients who do not have chronic pain or those who are not Veterans may not benefit from this research.

What this research studies

This research investigates the relationship between physical activity and pain levels in individuals with chronic pain, particularly focusing on cognitive behavioral interventions like Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT). By using accelerometers to objectively measure physical activity and ecological momentary assessment (EMA) to track pain in real-time, the study aims to provide insights into how these factors interact over time. The research specifically targets Veterans, a group that experiences high rates of chronic pain, to explore how cognitive behavioral strategies can modify this relationship. The goal is to enhance the effectiveness of pain management interventions by understanding the dynamics of pain and activity.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies that enhance physical functioning and quality of life for patients with chronic pain.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between physical activity and pain using similar methodologies, indicating that this approach has potential for success.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Tynan, Mara — University of California, San Diego
  • Study coordinator: Tynan, Mara

Related research

Other NIH-funded projects on the same topics.

  • Motor cortex tricks to ease chronic pain

    A study in rodents and people tests whether non-invasive brain stimulation of the motor cortex can reduce chronic pain and how best to target it.

    NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11621209

  • Human pain center study to map normal and migraine-trigeminal neurons

    A large NIH-funded project will map and study the human trigeminal neurons involved in migraines to understand what changes in these cells during headache conditions.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11615140

  • Understanding human pain neurons to improve migraine care

    Researchers are studying human pain-sensing neurons to uncover what makes migraine start and persist, with the goal of better treatments for people who experience migraines.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11615139

  • Whole Person Pain Algorithm to personalize chronic pain care

    A new, evidence-based model helps explain why chronic low back pain affects people differently and could guide personalized diagnosis and treatment.

    NIH research University of Florida · Gainesville, United States · NIH-11609318

  • Understanding how to use pharmacogenomic testing to guide chronic pain care

    This grant looks at how doctors who treat long‑term pain decide when and how to use genetic testing to tailor pain medicines for safer and more effective care.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11602241

  • Mindfulness and Self-Hypnosis for Pain in Older Adults

    This grant tests non-drug ways like mindfulness and self-hypnosis to help people over 60 manage chronic pain.

    NIH research University of Washington · Seattle, United States · NIH-11599794

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.