Understanding how physical activity affects heart health in older women

Objective Physical Activity and Cardiovascular Health in Older Women: OPACH2

NIH-funded research University of California, San Diego · NIH-10877830

This study is looking at how staying active affects heart health in women who are 85 and older, to see if even light activities can help lower the risk of heart disease and improve overall health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10877830 on NIH RePORTER

What this research studies

This research investigates the relationship between physical activity and cardiovascular health specifically in women aged 85 and older. By using accelerometers to objectively measure physical activity levels and sedentary behavior, the study aims to identify how different levels of activity impact the risk of cardiovascular disease and overall mortality. The research builds on previous findings that suggest even light physical activity can significantly reduce the risk of heart disease in older women. Participants will be monitored over time to assess changes in their health related to their activity levels.

Who could benefit from this research

Good fit: Ideal candidates for this research are women aged 85 and older who are interested in understanding how their physical activity levels affect their heart health.

Not a fit: Patients who are younger than 85 or those who are unable to engage in any physical activity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved guidelines for physical activity that enhance heart health and reduce mortality in older women.

How similar studies have performed: Previous studies have shown significant benefits of physical activity on cardiovascular health in older populations, indicating that this approach is supported by existing evidence.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.