Understanding how peroxisomes are formed and function in cells
Peroxisome biogenesis, dynamics, and degradation
['FUNDING_OTHER'] · RICE UNIVERSITY · NIH-11005386
This study is looking at how tiny parts of plant cells called peroxisomes are made, kept in good shape, and recycled, which could help us understand how plants stay healthy and protect themselves from damage.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RICE UNIVERSITY (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11005386 on ClinicalTrials.gov |
What this research studies
This research investigates the formation, maintenance, and recycling of peroxisomes, which are essential organelles in cells. Using the plant model Arabidopsis thaliana, the study aims to uncover how peroxisomes originate, how they interact with other organelles, and how they maintain their quality. The research employs advanced genetic, biochemical, and cell biological techniques to explore these processes, which could lead to a better understanding of metabolic efficiency and oxidative damage protection in cells.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with metabolic disorders, particularly those related to aging and diabetes.
Not a fit: Patients with conditions unrelated to metabolic processes or peroxisome dysfunction may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into metabolic disorders and age-related diseases, potentially improving treatment strategies for conditions like adult-onset diabetes.
How similar studies have performed: While the specific focus on peroxisome dynamics in plants is novel, related research on organelle function has shown promising results in understanding cellular processes.
Where this research is happening
HOUSTON, UNITED STATES
- RICE UNIVERSITY — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARTEL, BONNIE — RICE UNIVERSITY
- Study coordinator: BARTEL, BONNIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus, age associated disease, age associated disorder, age dependent disease