Understanding how people with schizophrenia make decisions about effort and rewards

Computational Mechanisms of Effort-Cost Decision-Making in Schizophrenia

NIH-funded research University of Maryland Baltimore · NIH-10863913

This study is looking at how people with schizophrenia think about the effort needed to get rewards, which can impact their motivation and daily life, and it compares their decision-making to that of healthy individuals to find ways to help improve motivation.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10863913 on NIH RePORTER

What this research studies

This research investigates how individuals with schizophrenia evaluate the effort required to achieve rewards, which can affect their motivation and daily functioning. By comparing decision-making processes between those with schizophrenia and healthy individuals, the study aims to identify whether these individuals are less sensitive to rewards or more sensitive to the effort involved. The research employs experimental tasks and computational modeling to analyze these decision-making mechanisms, potentially leading to better-targeted interventions for motivational impairments. Mobile-based assessments will also be utilized to gather real-time data on participants' decision-making in everyday situations.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia who experience motivational deficits.

Not a fit: Patients without a diagnosis of schizophrenia or those who do not experience motivational impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for motivational impairments in individuals with schizophrenia, enhancing their quality of life and occupational functioning.

How similar studies have performed: Previous research has indicated that understanding decision-making processes in mental health can lead to significant advancements in treatment, suggesting that this approach has potential for success.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.