Understanding how people value physical effort in health and disease

Subjective Valuation of Physical Effort in Health and Disease

NIH-funded research Hugo W. Moser Res Inst Kennedy Krieger · NIH-10661579

This study is looking at how people with conditions like multiple sclerosis feel about the effort they need to put into rehab therapies, especially when they’re dealing with fatigue, to help create better treatment plans that match their experiences.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHugo W. Moser Res Inst Kennedy Krieger NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10661579 on NIH RePORTER

What this research studies

This research investigates how individuals perceive and value physical effort, particularly in the context of rehabilitation therapies. It focuses on understanding why some patients, especially those with conditions like multiple sclerosis, may struggle to exert the necessary effort due to feelings of fatigue or overwhelming difficulty. By using advanced techniques such as brain imaging and noninvasive brain stimulation, the study aims to uncover the underlying mechanisms that influence these subjective valuations of effort. The findings could help improve rehabilitation strategies by tailoring them to better align with patients' perceptions of effort.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with neurological conditions, particularly those experiencing fatigue or difficulty with physical exertion.

Not a fit: Patients without neurological conditions or those who do not experience issues related to physical effort may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective rehabilitation therapies that enhance patient compliance and outcomes.

How similar studies have performed: Other research has shown promise in understanding effort-based judgments in various neurological conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.