Understanding how people adapt to losing a loved one

The neuromolecular basis of adaptation to bond loss

NIH-funded research University of Colorado · NIH-11003772

This study looks at how the brain and body help us cope with losing someone we love, using prairie voles as a model, to find ways to better support people dealing with grief.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado NIH-funded
Lab location1 site (Boulder, UNITED STATES)
Project IDNIH-11003772 on NIH RePORTER

What this research studies

This research investigates the biological and neural processes that help individuals adapt to the loss of a loved one, which can lead to physical and mental health issues. By studying prairie voles, which form strong pair bonds, researchers will simulate the experience of loss and observe how these animals respond behaviorally and molecularly over time. The study aims to identify the key changes in the brain that occur during the adaptation process, which could help improve support for those struggling with bereavement.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced the loss of a loved one and are struggling to adapt to that loss.

Not a fit: Patients who have not experienced a significant loss or those who are not currently facing bereavement may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better interventions and support systems for individuals experiencing grief, potentially reducing the risk of long-term health issues.

How similar studies have performed: While the specific approach of using prairie voles to study bereavement is novel, related research has shown success in understanding the biological impacts of loss and adaptation in other contexts.

Where this research is happening

Boulder, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.