Understanding how people adapt their vision after losing central sight

The preferred retinal locus in central vision loss

NIH-funded research University of California Berkeley · NIH-11049829

This study is looking at how people with central vision loss, like from age-related macular degeneration, learn to use their side vision instead, and it aims to find out how they can make the best use of it to improve their daily activities and overall quality of life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley NIH-funded
Lab location1 site (Berkeley, United States)
Project IDNIH-11049829 on NIH RePORTER

What this research studies

This research investigates how individuals with central vision loss, particularly from age-related macular degeneration, adapt by using their peripheral vision. It focuses on identifying the new retinal location, known as the preferred retinal locus (PRL), that patients use for visual tasks. The study aims to understand the mechanisms behind the development of the PRL and its effectiveness for various visual tasks, which could lead to improved rehabilitation strategies for those affected. By examining the properties of the PRL, researchers hope to enhance the quality of life for patients with central vision loss.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing central vision loss due to age-related macular degeneration.

Not a fit: Patients with intact central vision or those whose vision loss is not related to macular degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide new strategies for visual rehabilitation, helping patients regain better functional vision.

How similar studies have performed: Previous research has shown promise in understanding visual adaptation in patients with central vision loss, suggesting that this approach could yield valuable insights.

Where this research is happening

Berkeley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age related macular disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.