Understanding how patient factors affect pain relief from bone marrow treatments for osteoarthritis
Assessing the Impact of Patient Factors on Therapeutic Capabilities of BMAC for Osteoarthritic Pain
This study is looking at how things like your age, gender, and whether you have post-traumatic osteoarthritis can affect how well bone marrow injections help with joint pain, and it aims to find better, personalized ways to make these treatments work for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Decatur, UNITED STATES) |
| Project ID | NIH-11055444 on NIH RePORTER |
What this research studies
This research investigates how factors such as age, sex, and the presence of post-traumatic osteoarthritis (PTOA) influence the effectiveness of bone marrow aspirate concentrate (BMAC) injections for relieving joint pain. The study aims to develop personalized treatment strategies that may enhance the efficacy of BMAC by considering individual patient characteristics. By using a preclinical model, the research will explore how endurance exercise might prepare bone marrow to improve its therapeutic potential. Patients may be involved in trials that assess these personalized approaches to pain management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who experience osteoarthritic pain, particularly those with a history of post-traumatic osteoarthritis.
Not a fit: Patients who are younger than 65 or do not have osteoarthritis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain relief treatments for patients suffering from osteoarthritis.
How similar studies have performed: Previous research has shown promise in using autologous cell-based therapies for joint pain, suggesting that this approach may yield beneficial results.
Where this research is happening
Decatur, UNITED STATES
- Veterans Health Administration — Decatur, United States (Active)
Researchers
- Principal investigator: Kaiser, Jarred — Veterans Health Administration
- Study coordinator: Kaiser, Jarred
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.