Understanding how Parkinson's disease affects melanoma growth
Neural Mechanisms Driving Comorbid Parkinson's and Melanoma
This study is looking at how Parkinson's disease might affect the growth of melanoma, a type of skin cancer, by exploring the role of nerves in tumors, and it's aimed at helping people with Parkinson's understand how their condition could influence cancer development.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10880446 on NIH RePORTER |
What this research studies
This research investigates the connection between Parkinson's disease and melanoma, focusing on how the sympathetic nervous system may influence cancer progression. By studying mice with a specific genetic mutation linked to Parkinson's, researchers aim to understand how changes in nerve activity within tumors can alter melanoma growth. The project involves characterizing tumor development and the surrounding nerve environment in these mice to uncover potential mechanisms at play. This could lead to insights into how Parkinson's disease may impact cancer outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with both Parkinson's disease and melanoma.
Not a fit: Patients without Parkinson's disease or melanoma are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing melanoma in patients with Parkinson's disease.
How similar studies have performed: While there is limited research on this specific comorbidity, studies have shown promising results in understanding the interactions between the nervous system and cancer growth.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Del Valle, Pamela — Icahn School of Medicine at Mount Sinai
- Study coordinator: Del Valle, Pamela
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.