Understanding how parent and youth characteristics affect growth hormone treatment decisions and quality of life for short stature

A new paradigm of short stature: Incorporating parent and youth characteristics into understanding GH-related decision making and trajectories of quality of life and self-esteem

['FUNDING_R01'] · CHILDREN'S HOSP OF PHILADELPHIA · NIH-10559490

This study is looking at how both parents and kids make choices about growth hormone treatment for children who are shorter than average, focusing on how these decisions affect the kids' happiness and self-esteem, so we can find better ways to support them and their families.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCHILDREN'S HOSP OF PHILADELPHIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10559490 on ClinicalTrials.gov

What this research studies

This research investigates how the characteristics of both parents and youth influence the decision-making process regarding growth hormone (GH) treatment for children with short stature. It aims to understand the psychosocial factors that affect quality of life and self-esteem in youth aged 8-14 years, rather than just focusing on height as the primary outcome. By following participants over two years, the study will gather qualitative and quantitative data to explore the relationship between height, psychosocial adjustment, and overall well-being. The findings could help tailor treatment approaches to better meet the needs of children and their families.

Who could benefit from this research

Good fit: Ideal candidates for this research are youth aged 8-14 years who are being evaluated for growth hormone treatment due to short stature.

Not a fit: Patients who are not experiencing short stature or those outside the age range of 8-14 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that enhance the quality of life and self-esteem for children with short stature.

How similar studies have performed: Previous research has indicated that psychosocial factors significantly influence treatment decisions and outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.