Understanding how pancreatic cancers use metabolism to grow
Identifying Metabolic Dependencies of Pancreatic Cancers
This study is looking at how a tough type of pancreatic cancer changes its energy use to survive and grow, with the hope of finding new ways to treat it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889178 on NIH RePORTER |
What this research studies
This research investigates pancreatic ductal adenocarcinoma (PDAC), a highly aggressive cancer that is often diagnosed late and resistant to treatment. The team is exploring how these tumors adapt their metabolism to thrive in challenging environments, focusing on the role of specific genetic mutations and metabolic pathways. By utilizing innovative mouse models, they aim to identify critical metabolic processes that support tumor growth and survival. The findings could lead to new therapeutic strategies targeting these metabolic dependencies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma who may benefit from new treatment approaches.
Not a fit: Patients with other types of cancer or those who are not diagnosed with pancreatic ductal adenocarcinoma may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to novel treatments that specifically target the metabolic vulnerabilities of pancreatic cancer, improving patient outcomes.
How similar studies have performed: Previous research has shown promising results in targeting metabolic pathways in cancer, suggesting that this approach could be effective for pancreatic cancer as well.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Kimmelman, Alec — New York University School of Medicine
- Study coordinator: Kimmelman, Alec
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.