Understanding how pancreatic cancer evolves to improve treatment options
Interrogating the Evolutionary Dynamics of Cancer for Clinical Benefit and Actionability
This study is looking at how pancreatic cancer changes over time to find better ways to treat it, helping patients live longer by understanding both the cancer cells and their surroundings.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10893609 on NIH RePORTER |
What this research studies
This research investigates the evolutionary dynamics of pancreatic cancer to identify new treatment strategies. By analyzing genetic and transcriptional variations within tumors, the study aims to uncover how these changes affect cancer progression and response to therapies. The researchers will explore how both tumor cells and their surrounding environment contribute to cancer evolution, and how existing treatments can be optimized based on these insights. This approach seeks to develop more effective therapies that can extend survival for patients with pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic cancer, particularly those with advanced stages of the disease.
Not a fit: Patients with non-cancerous conditions or those with early-stage pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, potentially improving survival rates.
How similar studies have performed: Other research has shown promise in using evolutionary approaches to understand cancer dynamics, suggesting potential for success in this novel application.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Iacobuzio-Donahue, Christine a — Sloan-Kettering Inst Can Research
- Study coordinator: Iacobuzio-Donahue, Christine a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.