Understanding how pancreatic cancer cells move and spread
Full Project 1: Defining Mechanisms of MICAL-dependent Pancreatic Cancer Cell Migration
This study is looking at how pancreatic cancer cells move and spread in the body, especially focusing on the role of certain genes, to find new ways to treat this disease, particularly for African American and Hispanic patients who are more affected by it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10929485 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms behind the movement and spread of pancreatic cancer cells, particularly focusing on how certain genes influence these processes. By studying the differences between pancreatic cancer cells and normal cells, the researchers aim to identify potential therapeutic targets that could lead to more effective treatments. The project combines expertise in cancer biology with advanced modeling of cellular behavior to uncover insights that could improve patient outcomes. The research specifically addresses the challenges faced by African American and Hispanic patients who are disproportionately affected by pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic duct adenocarcinoma, particularly those from African American and Hispanic backgrounds.
Not a fit: Patients with other types of cancer or those without a diagnosis of pancreatic duct adenocarcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve survival rates for patients with pancreatic cancer.
How similar studies have performed: Previous research has shown promise in understanding cancer cell migration and targeting specific genes, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Lowy, Andrew M — University of California, San Diego
- Study coordinator: Lowy, Andrew M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.