Understanding how palliative care can help patients with blood cancers receiving advanced cell therapies
Official title: Defining the Role of Palliative care for Patients with Hematologic Malignancies Undergoing Adoptive Cellular Therapy
Funded at Massachusetts General Hospital · NIH-10807436 · Data updated 2026-11-12
This study is looking to make life better for patients with blood cancers who are getting CAR T-cell therapy by testing a new supportive care program called PEACE, which aims to help manage their symptoms and improve their overall experience, especially towards the end of life.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 16, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $293,053 |
| NIH project number | 1K08CA279772-01A1 |
| Project ID | NIH-10807436 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with hematologic malignancies who are receiving adoptive cellular therapies.
✕Less likely to help
Patients with solid tumors or those not undergoing adoptive cellular therapies may not benefit from this research.
What this research studies
This research focuses on improving the quality of life for patients with hematologic malignancies who are undergoing adoptive cellular therapies, such as CAR T-cell therapy. It aims to address the significant symptom burden and healthcare challenges these patients face, particularly at the end of life. By refining and testing a specialized palliative care intervention called PEACE, the study seeks to better meet the unique needs of these patients and their caregivers. The approach involves collaboration with palliative care clinicians to enhance support and care strategies tailored to this population.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and end-of-life care for patients undergoing complex cancer treatments.
How similar studies have gone: Previous studies have shown that integrating palliative care in oncology can improve outcomes, suggesting potential success for this tailored approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Johnson, Patrick Connor — Massachusetts General Hospital
- Study coordinator: Johnson, Patrick Connor
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.