Understanding how pain changes from acute to chronic
Official title: PSP Omics Center of Acute to Chronic Pain Signatures
Funded at Battelle Pacific Northwest Laboratories · NIH-10897968 · Data updated 2026-11-12
This study is looking at how to tell the difference between short-term pain and long-lasting pain by finding specific markers in your body, and it’s for patients who have experienced acute pain to help improve future pain management and prevention.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | September 1, 2019 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $536,927 |
| NIH project number | 5U54DA049116-06 |
| Project ID | NIH-10897968 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing acute pain who may be at risk of developing chronic pain.
✕Less likely to help
Patients with chronic pain conditions that are not related to acute pain episodes may not benefit from this research.
What this research studies
This research investigates the biological signatures that differentiate acute pain from chronic pain. By analyzing various omics data, the study aims to identify specific markers that can help predict which patients are at risk of developing chronic pain after an acute episode. Patients may be involved in providing biological samples or data that contribute to understanding these pain transitions. The goal is to develop better strategies for pain management and prevention based on individual patient profiles.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatments that prevent acute pain from becoming chronic, improving quality of life for many patients.
How similar studies have gone: While the approach of using omics data to study pain transitions is innovative, similar research has shown promise in identifying biomarkers for other conditions.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Jacobs, Jon — Battelle Pacific Northwest Laboratories
- Study coordinator: Jacobs, Jon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.