Understanding how pain affects men and women differently
Sexually dimorphic pain signaling mechanisms
This study is looking at how chronic pain conditions affect people differently based on their gender, and it aims to better understand how these pain issues can happen together and impact overall health and daily life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10890697 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind chronic overlapping pain conditions (COPCs) that affect many individuals, particularly focusing on how these conditions differ between biological males and females. By analyzing clinical, biological, and psychological factors, the study aims to identify distinct patient clusters that experience multiple pain conditions simultaneously. The goal is to enhance our understanding of how these pain conditions co-occur and impact overall health, including mental well-being and daily functioning.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing multiple chronic pain conditions, particularly those who identify as biological females.
Not a fit: Patients who do not have chronic pain conditions or those who are not experiencing comorbid pain issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for individuals suffering from chronic pain conditions.
How similar studies have performed: Previous research has shown promising results in understanding pain mechanisms, but this specific focus on sex differences in COPCs is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Donnelly, Christopher Ryan — Duke University
- Study coordinator: Donnelly, Christopher Ryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.