Understanding how oxytocin influences friendships and social bonds

Mechanisms supporting selective affiliation between peers

NIH-funded research University of California Berkeley · NIH-11084508

This study is looking at how a special brain chemical called oxytocin helps prairie voles, which are social animals like us, form friendships and connect with familiar partners while staying away from strangers.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley NIH-funded
Lab location1 site (Berkeley, United States)
Project IDNIH-11084508 on NIH RePORTER

What this research studies

This research investigates the role of the neuropeptide oxytocin in forming selective social bonds among peers, particularly in prairie voles, which have social structures similar to humans. By examining how oxytocin affects the acceptance of familiar partners and the avoidance of strangers, the study aims to uncover the biological mechanisms behind friendship formation. The researchers will use a combination of neuropharmacological and genetic techniques to manipulate oxytocin signaling and observe its effects on social behavior. This could provide insights into how social relationships are formed and maintained in both animals and humans.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with autism spectrum disorder or those experiencing difficulties in forming social connections.

Not a fit: Patients who do not have social affiliation challenges or those without conditions related to social bonding may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing social relationships and addressing social deficits in conditions like autism.

How similar studies have performed: Previous research has shown promising results regarding the role of oxytocin in social bonding, suggesting that this approach could yield valuable insights.

Where this research is happening

Berkeley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions autism spectral disorderautism spectrum disorderAutistic Disorderautistic spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.