Understanding how oxylipins affect health and disease
Official title: Mechanisms regulating the biosynthesis and signaling of oxylipins
Funded at Cincinnati Childrens Hosp Med Ctr · NIH-11095850 · Data updated 2026-11-12
This study is looking into how certain natural fats in our body, called oxylipins, affect health issues like inflammation, cancer, and heart disease, with the goal of finding better ways to diagnose and treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $401,250 |
| NIH project number | 5R35GM150691-03 |
| Project ID | NIH-11095850 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from inflammatory conditions, cancer, or cardiovascular diseases.
✕Less likely to help
Patients with conditions unrelated to oxylipin signaling or those not experiencing inflammation or cardiovascular issues may not benefit from this research.
What this research studies
This research investigates the role of oxylipins, which are bioactive lipids that play crucial roles in various health conditions, including inflammation, cancer, and cardiovascular diseases. The study aims to uncover the mechanisms that regulate the production and signaling of these molecules in the body. By identifying how oxylipins are synthesized and how they influence biological functions, the research seeks to bridge the gap between laboratory findings and clinical applications. This could lead to improved diagnostic and therapeutic strategies for diseases linked to oxylipins.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and treatments for conditions like cancer and cardiovascular diseases.
How similar studies have gone: Previous research has shown promising results in understanding the role of oxylipins in various diseases, indicating that this approach has potential for success.
Where this research is happening
-
Cincinnati Childrens Hosp Med Ctr
Cincinnati, United States Active
Researchers
- Principal investigator: Tourdot, Benjamin Eric — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Tourdot, Benjamin Eric
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.