Understanding how oxygen metabolism in the retina is affected by diabetic retinopathy
Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy
This study is looking at how oxygen use in the eye changes for people with diabetic retinopathy, a condition that can lead to vision loss, to help find out who might be at risk for serious eye problems and improve early treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10755672 on NIH RePORTER |
What this research studies
This research investigates the changes in oxygen metabolism in the retina of individuals with diabetic retinopathy (DR), a leading cause of vision loss among working-age adults. By employing advanced multimodal imaging techniques, the study aims to identify which diabetic patients are at risk of developing severe vision problems and how their oxygen metabolism is altered. The goal is to enhance early diagnosis and treatment strategies to prevent vision loss. Patients will be monitored over time to assess the relationship between oxygen levels and retinal health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with diabetes who are at risk of developing diabetic retinopathy.
Not a fit: Patients without diabetes or those who do not have any signs of diabetic retinopathy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for early diagnosis and treatment of diabetic retinopathy, potentially preserving vision for many patients.
How similar studies have performed: Previous research has shown that innovative imaging techniques can successfully identify metabolic changes in other conditions, suggesting potential for success in this novel approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Shahidi, Mahnaz — University of Southern California
- Study coordinator: Shahidi, Mahnaz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.