Understanding how our microbiome affects health

Characterizing human-microbiome interactions via molecular and functional genomic approaches

NIH-funded research Pennsylvania State University, the · NIH-10906935

This study is looking at the tiny germs in our bodies, like bacteria and viruses, to see how they affect our health and are influenced by our genes, helping us understand how our unique makeup can shape these microbial communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-10906935 on NIH RePORTER

What this research studies

This research investigates the complex ecosystems of microbes in the human body, including bacteria, archaea, and viruses, and how they influence health and disease. By examining the genetic factors that shape the microbiome, the research aims to uncover the connections between our genes and the composition of these microbial communities. The approach combines microbiome analysis with functional genomic techniques to explore how host genetics impacts the microbiota, particularly in areas adjacent to mucosal surfaces. This work seeks to fill critical gaps in our understanding of microbiome heritability and its implications for human health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in understanding the genetic factors that influence their microbiome and overall health.

Not a fit: Patients with no interest in genetic factors or microbiome health may not find this research beneficial.

Why it matters

Potential benefit: If successful, this research could lead to new insights into how our microbiome affects health, potentially informing personalized medicine approaches.

How similar studies have performed: Previous research has shown promising results in understanding the role of genetics in microbiome composition, indicating that this approach has potential for significant findings.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.