Understanding how our genes are organized and used
Regulation of chromatin dynamics
This research explores how the structure of our genetic material affects how our bodies use genes, which can impact diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-11088195 on NIH RePORTER |
What this research studies
Our bodies have a complex system for organizing our genes, called chromatin, which influences how our cells function. This project aims to uncover the specific 'machines' that help manage this genetic organization, ensuring our genes are used correctly. When these machines don't work properly, it can lead to various health problems, including cancer. By understanding these fundamental processes, we hope to find new ways to address diseases caused by genetic dysregulation.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation but aims to benefit patients with conditions like cancer in the future by uncovering disease mechanisms.
Not a fit: Patients seeking immediate new treatments or direct clinical interventions would not receive direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how diseases like cancer develop and potentially open doors for new treatment strategies.
How similar studies have performed: Previous genetic experiments have shown that these 'chromatin remodeling enzymes' are crucial for many cellular processes, and their malfunction is linked to various diseases.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Peterson, Craig L — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Peterson, Craig L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.