Understanding how our genes and gut bacteria interact
Population Genomics of Host-Microbiome Interactions
This study is looking at how our genes and the tiny microbes living in our bodies work together and affect our health, and it invites patients to help by sharing samples or information to better understand these connections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10847337 on NIH RePORTER |
What this research studies
This research investigates the complex relationships between human genetics and the diverse microbial communities in our bodies, known as the microbiome. It aims to uncover how variations in the microbiome are influenced by genetic factors and how these variations can affect health and disease. By analyzing both genetic and environmental influences over time, the research seeks to provide a clearer picture of how our microbiome interacts with our genes, potentially leading to new insights into disease mechanisms. Patients may be involved in providing samples or data to help map these interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with varying microbiome compositions, particularly those with conditions linked to gut health or genetic predispositions.
Not a fit: Patients with stable microbiomes and no genetic variations affecting their gut health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatments that consider both genetic makeup and microbiome composition, improving health outcomes.
How similar studies have performed: Previous research has shown promising results in understanding microbiome interactions, but this approach aims to provide deeper insights into genetic influences, making it a novel endeavor.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Blekhman, Ran — University of Chicago
- Study coordinator: Blekhman, Ran
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.