Understanding how our genes and environment affect health

Genetics as a tool to improve phenotypes and associations with human disease

NIH-funded research University of Colorado Denver · NIH-11187140

This project aims to understand how our genes and surroundings work together to influence various health conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11187140 on NIH RePORTER

What this research studies

The Cole Lab wants to use information from our genes to better understand how environmental factors contribute to human diseases. They are creating new ways to analyze and interpret health characteristics (phenotypes) and their connections to health markers. This work will help identify specific risk factors and the underlying processes that lead to disease. Ultimately, this will lead to better tools and resources for the scientific community to study how our environment impacts our health.

Who could benefit from this research

Good fit: This foundational research does not directly involve patient participation but aims to benefit individuals with various human diseases by improving our understanding of genetic and environmental risk factors.

Not a fit: Patients seeking immediate new treatments or direct clinical intervention would not find direct benefit from this foundational methods-focused research.

Why it matters

Potential benefit: If successful, this work could lead to a clearer understanding of disease causes, potentially guiding future prevention strategies and treatments.

How similar studies have performed: This project builds upon existing genetic and epidemiological methods, extending them with novel approaches to improve precision and interpretation.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.