Understanding how our body's internal clocks work
Spatiotemporal mechanisms controlling circadian rhythms
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10842068
This study looks at how our body's natural sleep and activity cycles work by exploring tiny brain cells in fruit flies, and it hopes to help us understand how problems with these cycles might affect our health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10842068 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that control circadian rhythms, which are the natural cycles that regulate sleep, metabolism, and other bodily functions. By studying clock neurons in fruit flies, the researchers aim to uncover how these internal clocks are organized and regulated at a cellular level. The approach involves examining the localization of clock proteins and genes within cells to understand their role in maintaining proper circadian rhythms. This knowledge could lead to insights into how disruptions in these rhythms contribute to various health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing health issues related to circadian rhythm dysregulation, such as sleep disorders, metabolic syndromes, or neurodegenerative diseases.
Not a fit: Patients with conditions unrelated to circadian rhythms or those who do not experience any rhythm-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating conditions related to circadian rhythm disruptions, such as diabetes, cancer, and neurodegenerative disorders.
How similar studies have performed: Previous research has shown promising results in understanding circadian rhythms, but this specific approach using Drosophila as a model system is relatively novel.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YADLAPALLI, SWATHI — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: YADLAPALLI, SWATHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers