Understanding how osteoporosis treatments work and why they may stop being effective.

Admin Core

['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11085954

This study is looking into how osteoporosis treatments work and why they might not be as effective over time, with the goal of finding better ways to help people with osteoporosis.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11085954 on ClinicalTrials.gov

What this research studies

This research aims to uncover the mechanisms behind osteoporosis anabolic therapies and why their effectiveness diminishes over time. By collaborating with a network of experts from prestigious institutions, the project will focus on the cellular and molecular actions of these treatments in humans. The Administrative Core will facilitate patient recruitment and support the scientific efforts of the research team, ensuring that findings are effectively communicated and utilized. Patients may be engaged in the process to help improve treatment strategies for osteoporosis.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with osteoporosis who are currently receiving or have received anabolic therapies.

Not a fit: Patients who do not have osteoporosis or those who are not undergoing anabolic therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved osteoporosis treatments that remain effective over time.

How similar studies have performed: Previous research has shown promise in understanding osteoporosis treatments, but this project aims to provide deeper insights into their mechanisms, making it a significant advancement in the field.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.