Understanding how organs adapt to changes in their environment
Official title: Multi-scale modulation of organ adaptation
Funded at University of Southern California · NIH-10842993 · Data updated 2026-11-12
This study looks at how birds' organs, especially their feathers, change and adapt to meet their needs as they grow and face different challenges, helping us understand how these changes happen at a cellular level.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $415,000 |
| NIH project number | 1R35GM153402-01 |
| Project ID | NIH-10842993 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in the biological mechanisms of organ adaptation and those with conditions affecting organ function.
✕Less likely to help
Patients with stable organ functions that do not require adaptation or those outside the age range of 21+ years may not benefit from this research.
What this research studies
This research investigates how organs, particularly in birds, adapt their functions and structures in response to changing physiological needs and external stimuli. By focusing on the avian integument, which includes feathers, the study aims to uncover the mechanisms behind organ adaptation at different life stages. The researchers will explore how stem cells and their environments interact to maintain organ performance while also allowing for changes. This approach combines molecular biology with environmental factors to understand organ modulation.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine and treatments for conditions related to organ function and adaptation.
How similar studies have gone: While the specific focus on avian integument is novel, similar research in organ adaptation has shown promising results in other contexts.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Chuong, Cheng-Ming — University of Southern California
- Study coordinator: Chuong, Cheng-Ming
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.