Understanding how organelles inside cells work together at a tiny scale
The dynamic architecture of living cells: Uncovering intra-organelle events at nanoscale levels
This study is looking at how tiny parts of our cells, especially the mitochondria, work together to keep our cells healthy, using special high-speed cameras to see what happens inside them in real-time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11014643 on NIH RePORTER |
What this research studies
This research investigates the intricate dynamics of organelles within living cells, focusing on the molecular events that occur inside these organelles, particularly mitochondria. By utilizing advanced high-speed super-resolution microscopy, the study aims to map cellular architecture in real-time and uncover how these organelles maintain cellular homeostasis. The research will explore the timing, distribution, and regulation of critical processes such as gene transcription and protein folding within mitochondria, which are essential for cellular function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular dysfunction, particularly those affecting mitochondrial health.
Not a fit: Patients with conditions unrelated to cellular or mitochondrial function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a deeper understanding of cellular processes that may inform treatments for degenerative neurologic disorders.
How similar studies have performed: While the approach of studying intra-organelle dynamics at the nanoscale is relatively novel, similar research has shown promise in enhancing our understanding of cellular processes.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Wong, Yvette — Northwestern University at Chicago
- Study coordinator: Wong, Yvette
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.