Understanding how organelles communicate with mitochondria
Official title: Molecular Dissection of Mitochondria-Organelle Interactions
Funded at University of Washington · NIH-10851148 · Data updated 2026-11-12
This study is looking at how mitochondria, the powerhouses of our cells, work with other parts of the cell in healthy people and how that changes in people with mitochondrial diseases, with the hope of finding new ways to help treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | August 15, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $95,702 |
| NIH project number | 3DP2ES032761-01S1 |
| Project ID | NIH-10851148 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with mitochondrial diseases or related metabolic disorders.
✕Less likely to help
Patients with conditions unrelated to mitochondrial dysfunction may not receive any benefit from this research.
What this research studies
This research investigates the interactions between mitochondria and other organelles in healthy cells and how these interactions change in mitochondrial diseases. By using advanced imaging techniques and biochemical methods, the study aims to identify signals from other organelles that regulate mitochondrial function. This could lead to new therapeutic strategies for treating mitochondrial dysfunction. Patients may benefit from insights gained about the cellular mechanisms involved in their conditions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for mitochondrial diseases and improve patient outcomes.
How similar studies have gone: Other research has shown promising results in understanding organelle interactions, suggesting potential for breakthroughs in this area.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Sancak, Yasemin S — University of Washington
- Study coordinator: Sancak, Yasemin S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.