Understanding how oral microbes form communities and affect dental health
Oral microbial community structure and assembly: from molecule to microbiome
This study is looking at how certain bacteria in your mouth work together to form sticky layers called biofilms, which can affect your oral health, especially if you have gum issues like gingivitis or periodontitis, and it aims to help us find better ways to keep your mouth healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Albany NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10892305 on NIH RePORTER |
What this research studies
This research investigates the structure and assembly of oral microbial communities, focusing on how specific bacteria contribute to the formation of biofilms in the mouth. By using an in vitro model, researchers will analyze the interactions between different microbial species and their impact on oral health, particularly in relation to conditions like gingivitis and chronic periodontitis. The study employs advanced techniques such as metagenomic sequencing and systems imaging to gain insights into the molecular mechanisms behind biofilm development. Patients may benefit from a better understanding of how oral health can be maintained or improved through microbial management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing oral health issues, particularly those with gingivitis or chronic periodontitis.
Not a fit: Patients without any oral health concerns or those who have already undergone extensive dental treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating oral diseases, improving overall dental health.
How similar studies have performed: Previous research has shown promising results in understanding microbial communities in other contexts, suggesting potential for success in this area as well.
Where this research is happening
Albany, United States
- State University of New York at Albany — Albany, United States (Active)
Researchers
- Principal investigator: Valm, Alex M — State University of New York at Albany
- Study coordinator: Valm, Alex M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.