Understanding how oral HPV infection affects cancer risk in people living with HIV

Who could benefit from this research

What this research studies

This research investigates the factors that contribute to the higher rates of oral HPV infection and oropharyngeal cancers among individuals living with HIV, particularly focusing on Hispanic populations. By examining biological, clinical, and sociocultural elements, the study aims to uncover why these disparities exist and how they can be addressed. Participants will be part of a multicenter cohort study that collects data on various factors influencing HPV persistence and clearance rates. The findings could lead to improved prevention strategies for oral cancers in at-risk populations.

Why it matters

Where this research is happening

• Comprehensive Cancer Center/ Univ/pr
  San Juan, United States Active

Researchers

• Principal investigator: Ortiz, Ana Patricia — Comprehensive Cancer Center/ Univ/pr
• Study coordinator: Ortiz, Ana Patricia

Related research

Other NIH-funded projects on the same topics.

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  This project looks for DNA markers in people living with HIV in Nigeria to find who has or might develop HPV-related mouth and throat cancers.

  NIH research Northwestern University · Chicago, United States · NIH-11401243

• Antibodies and vaginal bacteria in HPV-related cervical changes

  This project looks at whether antibodies bind different vaginal bacteria in women with HPV or cervical cell changes to understand why some women develop more serious lesions.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11398821

• Oral bacteria, gum disease, and oral HPV in people living with HIV

  This project looks at how the mouth’s bacteria and gum disease relate to oral HPV in people with HIV, and what immune factors might be involved.

  NIH research Emory University · Atlanta, United States · NIH-11384763

• How HIV Treatment Might Change Oral HPV Risk

  A study explored how antiretroviral therapy for HIV could affect the mouth’s lining and the chance of catching oral HPV, with participants including people living with HIV on ART and people using ART for PrEP.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11352535

• Understanding how the penile cancer microbiome and p16 relate to HPV and outcomes across diverse patients

  This project will look at how the tiny microbes living in penile tumors, p16 protein levels, high-risk HPV, and clinical outcomes are connected across patients from different regions.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11302466

• Understanding how HIV medication affects oral HPV infection

  This research explores if medications for HIV or HIV prevention might make people more likely to get oral human papillomavirus (HPV) infections.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11193516

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.