Understanding How Opioid Exposure Before Birth Affects Babies
CWRU Clinical Center - Outcomes of Babies with Opioid Exposure (OBOE) Study
['FUNDING_OTHER'] · CASE WESTERN RESERVE UNIVERSITY · NIH-11145237
This project follows babies who were exposed to opioids before they were born to learn more about their brain development and overall growth.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11145237 on ClinicalTrials.gov |
What this research studies
This project carefully follows babies from birth until they are two years old, comparing those who were exposed to opioids before birth with those who were not. We gather detailed information, including samples from umbilical cords and advanced brain scans, to understand how early opioid exposure might affect their development. We also look at factors like the home environment and the mother's well-being to get a complete picture of each child's journey. The goal is to complete the follow-up for the existing group of infants to fulfill the main objectives of the project.
Who could benefit from this research
Good fit: This project previously enrolled infants with and without opioid exposure before birth and is now focused on continuing to follow them until they reach two years of age.
Not a fit: New patients cannot join this project as enrollment for infants has already been completed.
Why it matters
Potential benefit: This work could help us better understand how opioid exposure before birth impacts a child's brain and development, leading to improved support and care for these children.
How similar studies have performed: While previous studies have looked at this topic, this project uses improved methods and larger sample sizes to gather more comprehensive information.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILSON-COSTELLO, DEANNE E — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: WILSON-COSTELLO, DEANNE E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.