Understanding how older adults with acute myeloid leukemia fare with new treatments
Aging trajectories and outcomes of older adults with acute myeloid leukemia
This project looks at how new treatments for acute myeloid leukemia affect the daily lives and thinking abilities of older adults.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11129791 on NIH RePORTER |
What this research studies
Many older adults with acute myeloid leukemia (AML) worry about how treatment might impact their independence and mental sharpness. This project explores the real-world effects of a newer, less intensive chemotherapy combined with venetoclax on patients aged 60 and older. Researchers are observing changes in cognitive function, physical abilities, and overall quality of life after treatment. The goal is to better understand who might be at higher risk for declines and how to support patients through their treatment journey.
Who could benefit from this research
Good fit: Ideal candidates are older adults, aged 60 and above, who have been diagnosed with acute myeloid leukemia and are considering or undergoing newer treatments.
Not a fit: Patients who are not older adults or do not have acute myeloid leukemia would not directly benefit from this specific research.
Why it matters
Potential benefit: This work could help doctors better predict how new AML treatments affect older adults' daily lives and thinking, leading to more personalized care plans.
How similar studies have performed: Preliminary data from this team suggests that many older adults with AML maintain or improve their cognitive and physical function with newer treatments, despite some risk factors like frailty.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Bhatt, Vijaya Raj — University of Nebraska Medical Center
- Study coordinator: Bhatt, Vijaya Raj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.