Understanding how obesity develops in children from infancy to childhood

Neural and behavioral mechanisms of obesity development from infancy through childhood

NIH-funded research Johns Hopkins University · NIH-11062414

This study is looking at how different kids might be at risk for obesity based on their genes and their environment, and it uses brain scans to understand how these factors affect their eating habits and weight from a young age, with the goal of finding ways to help them develop healthier eating habits.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11062414 on NIH RePORTER

What this research studies

This research investigates the individual differences in obesity risk among children, focusing on how genetic and environmental factors influence appetitive behaviors that drive food intake and weight gain. By utilizing advanced MRI techniques, the study aims to uncover the neurodevelopmental mechanisms that contribute to variations in appetite and weight from infancy through early childhood. The research will analyze brain structures and functions related to appetite control and reward processing, providing insights into how these factors may lead to obesity as children grow. The findings could help identify critical periods for intervention to promote healthier eating habits and weight management.

Who could benefit from this research

Good fit: Ideal candidates for participation include children aged 0-11 years, particularly those with a family history of obesity or other risk factors.

Not a fit: Patients who are already diagnosed with obesity-related metabolic disorders may not directly benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for preventing and treating obesity in children, ultimately improving their long-term health outcomes.

How similar studies have performed: Previous research has shown promising results in understanding the neurodevelopmental aspects of obesity, suggesting that this approach could yield valuable insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.