Understanding how obesity affects COVID-19 and how COVID-19 impacts metabolism
Impact of obesity on SARS-CoV-2 infection and reciprocal effects of SARS-CoV-2 on metabolic disease
['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11117098
This project explores how having obesity changes the way your body responds to COVID-19, and how the virus itself might affect your metabolism.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11117098 on ClinicalTrials.gov |
What this research studies
We know that conditions like diabetes and heart disease, often linked to obesity, can make COVID-19 more severe. This work aims to find out if obesity alone, even without these other diagnoses, increases the risk of serious COVID-19 outcomes. Researchers are also looking into how COVID-19 might change your body's sugar and fat metabolism, potentially leading to new-onset diabetes or long-term health issues after recovery. Understanding these connections could help us better protect people with obesity from severe COVID-19 and manage its lasting effects.
Who could benefit from this research
Good fit: This research is relevant for adults aged 21 and older who have obesity and have been infected with SARS-CoV-2, or those interested in the metabolic effects of COVID-19.
Not a fit: Patients without obesity or those not affected by SARS-CoV-2 infection may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better strategies for preventing severe COVID-19 in people with obesity and for managing metabolic problems that arise after infection.
How similar studies have performed: While the link between obesity and severe respiratory disease is known, this project specifically explores the two-way relationship between obesity and SARS-CoV-2 infection, including long-term metabolic changes, which is a growing area of investigation.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROBERTS, CHARLES T — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: ROBERTS, CHARLES T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Disease