Understanding how obesity affects blood pressure regulation
Sympathetic neural patterns and transduction in obesity-associated hypertension
This study looks at how being overweight can affect blood pressure by exploring how stress impacts nerve signals that control blood vessels, and it aims to find new ways to help people with high blood pressure, especially those who are obese.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10908739 on NIH RePORTER |
What this research studies
This research investigates the relationship between obesity and hypertension by examining how sympathetic nervous activity influences blood pressure regulation. It focuses on the unique patterns of nerve signals that occur during stress and how these patterns may lead to increased blood vessel constriction. By studying these mechanisms in both animal models and humans, the research aims to identify new therapeutic targets for treating hypertension, particularly in individuals affected by obesity.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing hypertension, particularly those with obesity.
Not a fit: Patients who do not have hypertension or obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hypertension that are more effective for patients with obesity.
How similar studies have performed: Previous research has shown promising results in understanding sympathetic nervous activity and its role in hypertension, suggesting that this approach could yield valuable insights.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Hearon, Christopher M — Ut Southwestern Medical Center
- Study coordinator: Hearon, Christopher M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.