Understanding how nutrient demand and reward can influence aging

Modulation of aging through mechanisms of nutrient demand and reward

NIH-funded research University of Michigan at Ann Arbor · NIH-11123249

This study is looking at how our body's need for nutrients and our reward systems are connected to aging, with the hope of finding new ways to help prevent age-related diseases like cancer and dementia, which could benefit patients in the future.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11123249 on NIH RePORTER

What this research studies

This research investigates the biological mechanisms that link nutrient demand and reward systems to the aging process. By studying these connections, the project aims to uncover how they contribute to age-related diseases such as cancer and dementia. The approach involves using model organisms to explore the effects of specific genes and signaling pathways on aging and health outcomes. Patients may benefit from insights that could lead to new interventions targeting the aging process and associated diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing age-related health issues or those interested in the biological aspects of aging.

Not a fit: Patients who are not elderly or do not have age-related diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related diseases, improving overall health in older adults.

How similar studies have performed: Previous research has shown promising results in understanding aging mechanisms through similar biological approaches, indicating potential for success in this area.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.