Understanding how nuclei move within cells
Mechanisms of Nuclear Migration
This study looks at how certain proteins help move the nucleus of a cell to the right spot, which is important for things like how our immune system works and how cancer spreads, so we can better understand these processes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11010728 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that control the positioning of cell nuclei, which is crucial for various cellular functions and development. It focuses on the roles of specific protein complexes that connect the nucleus to the cytoskeleton, helping to direct nuclear movement along microtubules. By studying the interactions between these proteins and their effects on nuclear shape and movement, the research aims to fill gaps in our understanding of how nuclei navigate through cellular environments, which is important for processes like immune responses and cancer metastasis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cancer metastasis or immune response issues.
Not a fit: Patients with unrelated conditions or those not experiencing issues with nuclear positioning or related cellular processes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular processes that affect cancer progression and immune responses, potentially informing therapeutic strategies.
How similar studies have performed: While the specific mechanisms being investigated are novel, similar approaches in studying cellular movement and positioning have shown promise in other research.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Starr, Daniel a — University of California at Davis
- Study coordinator: Starr, Daniel a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.