Understanding how Notch proteins affect blood vessel growth
Official title: Investigating tyrosine phosphorylation of Notch proteins
Funded at Boise State University · NIH-10578301 · Data updated 2026-11-12
This study is looking at how certain proteins help control the growth of blood vessels, which is important for both healthy and sick people, and it also offers a chance for students to learn more about this exciting area of science.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boise State University NIH-funded |
| Lab location | 1 site (Boise, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2023 |
| Award (this year) | $408,339 |
| NIH project number | 1R15HL167130-01 |
| Project ID | NIH-10578301 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that affect blood vessel health, such as diabetes or vascular disorders.
✕Less likely to help
Patients with stable vascular health or those not experiencing any related disorders may not benefit from this research.
What this research studies
This research investigates the role of Notch proteins and their phosphorylation in regulating blood vessel formation, a process known as angiogenesis. By examining how these proteins interact with the extracellular matrix and integrins, the study aims to uncover new signaling mechanisms that influence cellular behavior in both healthy and diseased states. The research will involve laboratory techniques to analyze these interactions and their effects on vascular function, while also providing educational opportunities for students in the field of science.
Why it matters
Potential benefit: If successful, this research could lead to new insights into treatments for diseases related to blood vessel dysfunction, such as diabetes and fibrosis.
How similar studies have gone: Other research has shown promising results in understanding the role of Notch signaling in vascular biology, suggesting that this approach could yield valuable insights.
Where this research is happening
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Boise State University
Boise, United States Active
Researchers
- Principal investigator: Albig, Allan R — Boise State University
- Study coordinator: Albig, Allan R
Related research
Other NIH-funded projects on the same topics.
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Healthy Idaho Clinical & Translational Research Development Program
A multi-institution effort in Idaho to build clinical and translational research capacity and workforce to address local health needs.
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Healthy Idaho Health Research Core supports translational projects
A Boise State University program funds and guides health research projects in Idaho to turn ideas into bigger health improvements for local communities.
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Healthy Idaho Clinical and Translational Research Design and Data Management
A program to strengthen how clinical and translational studies are planned, run, and using health data across Idaho, helping researchers design better studies and use EHR data responsibly.
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Healthy Idaho community engagement for translational research
A Boise State University program aims to strengthen ties between researchers and Idaho communities to support research that meets local health needs.
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Healthy Idaho professional development for clinical and translational research
A program to help Idaho investigators build skills and mentoring networks to conduct high-quality clinical and translational research.
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Healthy Idaho Clinical & Translational Research Development Administrative Core
A funded administrative core in Idaho helps coordinate and support clinical and translational research to improve health across the state.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.