Understanding how non-coding RNAs regulate gene expression
Biophysics of Regulatory RNAs and RNPs
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10883616
This study is looking at tiny molecules called microRNAs to see how they help control genes and how changes in them might be linked to diseases like cancer, diabetes, and heart problems, so that patients can better understand their conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10883616 on ClinicalTrials.gov |
What this research studies
This research investigates the role of non-coding RNAs, particularly microRNAs, in regulating gene expression and their implications in various diseases such as cancer, diabetes, and heart disorders. The study aims to uncover the molecular mechanisms that control the processing of these microRNAs, focusing on both RNA structure and protein interactions. By exploring these regulatory pathways, the research seeks to provide insights into how deviations in microRNA levels can lead to disease. Patients may benefit from a better understanding of how these processes affect their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancers, diabetes, or heart diseases who are interested in understanding the molecular basis of their conditions.
Not a fit: Patients with conditions unrelated to microRNA dysregulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing diseases linked to microRNA dysregulation.
How similar studies have performed: Previous research has shown promising results in understanding the role of microRNAs in various diseases, indicating that this approach has potential for significant findings.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KEANE, SARAH COURTNEY — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: KEANE, SARAH COURTNEY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer, diabetes, Diabetes Mellitus