NIH-funded research NIH-funded research

Understanding how noise exposure affects hearing pathways

Official title: Signal Processing Along the Auditory Pathway: Changes Following Noise Exposure

Funded at Veterans Health Administration · NIH-11277039 · Data updated 2026-11-12

This study is looking at how noise and blasts affect hearing in military personnel, aiming to understand the different types of damage that can happen to the ears so that we can improve how we diagnose and treat hearing loss.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration
NIH-funded
Lab location1 site (Long Beach, United States)
Project startJanuary 1, 2023
Project endDecember 31, 2026
Funding year2025
NIH project number7I01RX003491-04
Project IDNIH-11277039 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are military personnel or individuals who have experienced noise or blast exposure and are suffering from hearing loss.

Less likely to help

Patients with hearing loss not related to noise or blast exposure may not benefit from this research.

What this research studies

This research investigates the impact of noise and blast exposure on the auditory system, particularly focusing on sensorineural hearing loss (SNHL) in military personnel. By utilizing advanced techniques like optical coherence tomography (OCT) alongside existing clinical measures, the study aims to differentiate between sensory and neural damage in the auditory pathway. This approach will help in better diagnosing hearing loss and understanding the underlying mechanisms of auditory damage. The goal is to improve clinical assessments and potentially lead to better management strategies for affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods for hearing loss, allowing for more tailored treatment options for patients.

How similar studies have gone: While the approach of using OCT in humans is novel, similar methodologies have shown promise in animal studies, indicating potential for success in this research.

Where this research is happening

  • Veterans Health Administration
    Long Beach, United States
    Active

Researchers

  • Principal investigator: Dong, Wei — Veterans Health Administration
  • Study coordinator: Dong, Wei

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.