Understanding How NNAT Affects Body Metabolism
NNAT in metabolic regulation
This project explores how a protein called Nnat influences how our bodies burn fat to find new ways to help with obesity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11118870 on NIH RePORTER |
What this research studies
Obesity is a serious health concern, and while many current treatments focus on reducing appetite, this project looks at an alternative: increasing how much energy our bodies burn. Humans have special types of fat, called brown and beige fat, that can generate heat and burn calories. This research focuses on a protein named Nnat, which appears to stop these fat cells from burning energy. We aim to understand how Nnat controls the body's energy use and sugar balance, and how it interacts with other cellular components to impact fat burning.
Who could benefit from this research
Good fit: This foundational laboratory research is not directly recruiting patients but aims to benefit individuals living with obesity in the future.
Not a fit: Patients not living with obesity or related metabolic conditions may not directly benefit from this specific line of research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity that work by helping the body burn more calories.
How similar studies have performed: While other mechanisms for burning fat have been explored, the specific role of the Nnat protein as an inhibitor of fat burning is a new area of focus.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Yoon, John C — University of California at Davis
- Study coordinator: Yoon, John C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.