Understanding how nicotine in electronic cigarettes affects public health
Official title: Administrative Core (AC)
Funded at Ohio State University · NIH-10929379 · Data updated 2026-11-12
This study is looking at how different levels of nicotine in e-cigarettes and nicotine pouches affect how attractive and addictive they are, especially for young people, while also helping to create safer options for adults who use tobacco.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 14, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $274,904 |
| NIH project number | 5U54CA287392-02 |
| Project ID | NIH-10929379 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults who currently use tobacco products and young individuals who are at risk of starting to use electronic cigarettes or nicotine pouches.
✕Less likely to help
Patients who do not use tobacco products and are not at risk of nicotine addiction may not benefit from this research.
What this research studies
This research focuses on how the manipulation of nicotine in electronic cigarettes and oral nicotine pouches impacts their appeal, addictiveness, and toxicity. The Administrative Core will facilitate collaboration among researchers to gather and analyze data on these products, aiming to inform effective regulations and standards. By understanding these factors, the research seeks to dissuade young people from using these products while providing safer alternatives for adult tobacco users. The core will also ensure that all activities are aligned with the overall goal of maximizing public health.
Why it matters
Potential benefit: If successful, this research could lead to improved regulations that reduce nicotine addiction among young people while offering safer options for adult smokers.
How similar studies have gone: Previous research has shown success in understanding nicotine's effects on addiction and product appeal, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wagener, Theodore Lee — Ohio State University
- Study coordinator: Wagener, Theodore Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.